What is HER2/neu testing?
Listen to pronunciation. A laboratory test that measures the amount of HER2/neu protein on cancer cells or how many copies of the HER2/neu gene are in the DNA of cancer cells. The HER2/neu protein helps control normal cell growth.
What are ER PR and HER2?
ER = estrogen receptor, Her2 = human epidermal growth factor receptor 2, PR = progesterone receptor.
What is the function of HER2 receptor?
HER2 proteins are receptors on breast cells. Normally, HER2 receptors help control how a healthy breast cell grows, divides, and repairs itself. But in about 10% to 20% of breast cancers, the HER2 gene doesn’t work correctly and makes too many copies of itself (known as HER2 gene amplification).
What percentage of breast cancer is hormone receptor positive?
About 70-80 percent of breast cancers are hormone receptor-positive [18,29]. Hormone receptor status is part of breast cancer staging and helps guide your treatment. You may hear the term “biomarker” to describe hormone receptors.
What does neu test mean?
Neutrophils are a type of white blood cell. In fact, most of the white blood cells that lead the immune system’s response are neutrophils. There are four other types of white blood cells. Neutrophils are the most plentiful type, making up 55 to 70 percent of your white blood cells.
What is a hormone receptor test?
(HOR-mone reh-SEP-ter test) A test to measure the amount of certain proteins, called hormone receptors, in cancer tissue. Hormones can attach to these proteins. A high level of hormone receptors may mean that hormones help the cancer grow.
What is hormone receptor positive?
Listen to pronunciation. (HOR-mone reh-SEP-ter PAH-zih-tiv) Describes cells that have a group of proteins that bind to a specific hormone. For example, some breast cancer cells have receptors for the hormones estrogen or progesterone.
Is it better to be hormone receptor-positive or negative?
Hormone receptor-positive cancers tend to grow more slowly than those that are hormone receptor-negative. Women with hormone receptor-positive cancers tend to have a better outlook in the short-term, but these cancers can sometimes come back many years after treatment.
Is it better to have HER2-positive or HER2-negative?
Breast cancer cells with higher than normal levels of HER2 are called HER2-positive. These cancers tend to grow and spread faster than breast cancers that are HER2-negative, but are much more likely to respond to treatment with drugs that target the HER2 protein.
What does HER2/neu negative mean?
Listen to pronunciation. (… NEH-guh-tiv) Describes cells that have a small amount or none of a protein called HER2 on their surface.
What does hormone receptor positive mean?
(HOR-mone reh-SEP-ter PAH-zih-tiv) Describes cells that have a group of proteins that bind to a specific hormone. For example, some breast cancer cells have receptors for the hormones estrogen or progesterone. These cells are hormone receptor positive and they need estrogen or progesterone to grow.
Is it good to be HER2-positive or negative?
Is HER2 a hormone receptor?
Estrogen receptors (ER), progesterone receptors (PR), and epidermal growth factor (HER2) are prognostic and predictive factors for breast carcinoma.