What is the route of transmission of diphtheria?
Diphtheria is transmitted from person to person through close contact with the discharge from an infected person’s eyes, nose, throat or skin.
What is the portal of entry for diphtheria?
The most common portals of entry of the diphtheria bacillus are the tonsils, nose, and throat. The bacillus usually remains and propagates in that region, producing a powerful toxin that spreads throughout the body via the bloodstream and lymph vessels and damages the heart and the nervous system.
How does diphtheria enter the cell?
After binding HB-EGF, DT is translocated into cells via receptor-mediated endocytosis. Acidification of the endosome results in protein unfolding and insertion of a segment of the B subunit termed the ‘translocation region’ into the endosomal membrane.
How does diphtheria enter the body?
Diphtheria is caused by the bacterium Corynebacterium diphtheriae. The bacterium usually multiplies on or near the surface of the throat or skin.
What is the portal of entry?
PORTAL OF ENTRY The opening where an infectious disease enters the host’s body such as mucus membranes, open wounds, or tubes inserted in body cavities like urinary catheters or feeding tubes.
Is diphtheria a communicable disease?
Diphtheria is a highly contagious, infectious disease caused by a bacterium called Corynebacterium diphtheriae.
Which part of the body is affected by diphtheria?
The symptoms of diphtheria include suffocation, swollen lymph nodes in the neck, chills, fever, loud cough, bluish skin, difficulty in breathing, etc. The bacteria live in the mouth, throat, and nose of an infected person and can be passed to others by coughing or sneezing. So, the correct answer is option B.
Where did diphtheria originate from?
Diphtheria may be documented back to ancient Egypt and Greece, but severe recurring outbreaks begin only after 1700. One of every ten children infected died from this disease. Symptoms ranged from severe sore throat to suffocation due to a ‘false membrane’ covering the larynx.
Is Corynebacterium an STI?
Corynebacterium vaginale is a sexually transmitted organism which was first recognized in 1953. It appears to utilize glycogen stored in vaginal epithelial cells, causing a malodorous vaginal discharge characterized by an abnormally high pH (5.0 to 5.5) and composed mainly of epithelial cells and hordes of bacilli.
Is pertussis a droplet or airborne?
Pertussis is spread by respiratory droplets generated through coughing, sneezing and even talking. People with pertussis usually spread the disease while in close contact with others, who then breathe in the bacteria. An infected person is most contagious early in the course of illness.
Is pertussis airborne transmission?
pertussis occurs via aerosolized respiratory droplets, no controlled study has ever documented airborne transmission of pertussis.
Is diphtheria an STD?
While classical respiratory diphtheria is transmitted by droplets, cutaneous diphtheria often results from minor trauma. This report concerns the first case of sexually transmitted diphtheria in a patient with non-gonococcal urethritis after orogenital contact.