Can raloxifene cause osteonecrosis of jaw?
Raloxifene is a selective estrogen receptor modulator (SERM) that is used to manage osteoporosis in women. Because of its tissue selectivity, raloxifene has fewer side effects than estrogen therapy; however, raloxifene-associated osteonecrosis of the jaw (ONJ) has recently been reported.
Does raloxifene cause MRONJ?
Raloxifene has no known association with MRONJ.
Which osteoporosis medication causes osteonecrosis of the jaw?
Bisphosphonates — such as alendronate (Fosamax, Binosto), risedronate (Actonel, Atelvia), ibandronate (Boniva) and zoledronic acid (Reclast, Zometa) — and denosumab (Prolia, Xgeva) have been linked to osteonecrosis of the jaw and atypical femoral fractures.
What is a serious adverse effect that may occur with use of raloxifene?
Get medical help right away if you have any very serious side effects, including: signs of a blood clot (such as sudden pain/swelling/redness/warmth in the leg or arm, chest pain, trouble breathing, coughing up blood, sudden vision changes like blurred vision/loss of vision), signs of a stroke (such as weakness on one …
How long can you stay on Evista?
In research studying Evista to reduce breast cancer risk, women took the medicine for five years. Still, it’s not completely clear how long you should take Evista to get the most risk-reduction benefits. Depending on your unique situation, your doctor may prescribe Evista for more or less than five years.
Is prolia better than Evista?
Evista (raloxifene) helps to reduce bone loss and lower the risk of breast cancer in post-menopausal women, but it can cause blood clots. Prolia (Denosumab) is effective at preventing bone loss, making your bones stronger and lowering your chance of getting a fracture.
What are the long term effects of Evista?
The safety profile of EVISTA after four years of treatment was similar to that of EVISTA following three years of therapy. Additional adverse events (>2% and more common with EVISTA than with placebo) included hot flashes, leg cramps, swelling, flu-like symptoms, joint pain and sweating.
What are the long-term effects of Evista?
How long can you safely take Evista?