What is edetate calcium disodium used for?

Edetate calcium disodium is indicated for the reduction of blood levels and depot stores of lead in lead poisoning (acute and chronic) and lead encephalopathy, in both pediatric populations and adults. Chelation therapy should not replace effective measures to eliminate or reduce further exposure to lead.

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What is sodium edetate used for?

What is edetate disodium? Edetate disodium (EDTA) is a chelating (KEE-late-ing) agent. A chelating agent is capable of removing a heavy metal, such as lead or mercury, from the blood. EDTA is used to lower blood levels of calcium when they have become dangerously high.

What are the side effects of calcium disodium EDTA?

Side effects that you should report to your doctor or health care professional as soon as possible:

allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue.
cloudy or dark urine.
fast, irregular heartbeat.
fever, chills.
increased thirst.
low blood pressure.
numb, tingling pain.
tremors.

Is EDTA and edetate the same?

Sodium calcium edetate (sodium calcium EDTA), also known as edetate calcium disodium among other names, is a medication primarily used to treat lead poisoning, including both short-term and long-term lead poisoning. Sodium calcium edetate came into medical use in the United States in 1953.

Is calcium disodium EDTA safe?

EDTA can cause abdominal cramps, nausea, vomiting, diarrhea, headache, low blood pressure, skin problems, and fever. It is UNSAFE to use more than 3 grams of EDTA per day, or to take it longer than 5 to 7 days. Too much can cause kidney damage, dangerously low calcium levels, and death.

Is edetate disodium safe?

EDTA is safe when used as a prescription medicine, as eye drops, and in small amounts as a preservative in foods. EDTA can cause abdominal cramps, nausea, vomiting, diarrhea, headache, low blood pressure, skin problems, and fever.

Is disodium edetate safe?

Does EDTA lower blood pressure?

Is calcium disodium EDTA healthy?

Calcium disodium EDTA is found in food, cosmetic and industrial products and used to treat metal toxicity. The ADI is 1.1 mg per pound (2.5 mg per kg) of body weight per day — much higher than what is typically consumed. At these levels, it’s considered safe without serious side effects.

How long does EDTA stay in the body?

Lead poisoning and heavy metal toxicity Injected intravenously and once in the bloodstream, EDTA traps lead and other metals, forming a compound that the body can eliminate in the urine. The process generally takes 1 to 3 hours.

It’s a popular food additive, used as a preservative and flavoring agent. Calcium disodium EDTA works as a chelating agent. This means it binds to metals and prevents them from participating in chemical reactions that might cause discoloration or flavor loss.

Is edetate disodium the same as disodium EDTA?

Edetate disodium (EDTA) is a chelating (KEE-late-ing) agent. A chelating agent is capable of removing a heavy metal, such as lead or mercury, from the blood. EDTA is used to lower blood levels of calcium when they have become dangerously high.

Is calcium disodium EDTA harmful?

Is EDTA harmful to skin?

In several studies, the Cosmetics Review Board has found that as used in cosmetics products, disodium EDTA is safe. It was determined that in the concentrations used in commercial cosmetics, it is not a skin sensitizer nor a carcinogen, and does not penetrate through skin.

What is the difference between EDTA and calcium disodium EDTA?

The key difference between disodium EDTA and tetrasodium EDTA is that disodium EDTA has a pH lower than 7 while tetrasodium EDTA has a pH greater than 7. EDTA is a chelating agent. Therefore, it has the potential to bind with metal ions such as calcium and magnesium. EDTA stands for Ethylenediaminetetraacetic acid.

What is calcium disodium EDTA made of?

EDTA monocalcium diisodium salt is an organic calcium salt of EDTA diisodium. It is a chelating agent that is used for the treatment of lead poisoning. It has a role as a geroprotector, a chelator and an antidote. It contains an EDTA disodium salt (anhydrous).

Is disodium EDTA harmful?

In addition to being used in makeup, skin care, and hair care products, disodium EDTA is also used as a food additive. In several studies, the Cosmetics Review Board has found that as used in cosmetics products, disodium EDTA is safe.

Is EDTA harmful to humans?

Does EDTA cause hair loss?

Does EDTA cause hair loss? EDTA is not one of the ingredients in shampoo that causes hair loss.

Can EDTA unclog arteries?

Atherosclerosis. Evidence that EDTA chelation therapy is effective for heart disease is mixed. Proponents believe it may help people with atherosclerosis (hardening of the arteries) or peripheral vascular disease (decreased blood flow to the legs) by clearing clogged arteries and improving blood flow.

Is EDTA a carcinogen?

It is made from sodium cyanide and formaldehyde. The way Tetrasodium EDTA is considered suspect by many skincare agents. However, the compound is not considered a carcinogen.