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What is Hybrid Capture System?

What is Hybrid Capture System?

The hybrid capture technique is based on the formation of RNA-DNA hybrids between HPV DNA that may be present in clinical specimens and complementary unlabeled HPV RNA probes. The RNA-DNA hybrids are captured and immobilized by antihybrid antibodies.

What is Digene HPV DNA test?

The digene HC2 HPV DNA Test is an in vitro microplate assay based on signal-amplified nucleic acid hybridization that uses chemiluminescence for the qualitative detection of 18 types of human papillomavirus (HPV) DNA in cervical specimens.

Can you test for HPV at home?

A person can test themselves for human papillomavirus (HPV) with a home HPV test. Studies suggest that home HPV tests are as accurate as tests that doctors provide, but they may not test for all strains of HPV.

What type of assay is Hybrid Capture?

The HC2 High-Risk HPV DNA Test using Hybrid Capture®2 (HC2) technology is a nucleic acid hybridization assay with signal amplification using microplate chemiluminescence for the qualitative detection of thirteen high-risk types of human papillomavirus (HPV) DNA in cervical specimens.

How are you tested for HPV?

An HPV test is usually done at the same time as a Pap test — a test that collects cells from your cervix to check for abnormalities or the presence of cancer. An HPV test can be done using the same sample from the Pap test or by collecting a second sample from the cervical canal.

What is Hybrid Capture assays?

What is HPV PCR test?

Nucleic acid (DNA) testing by polymerase chain reaction (PCR) has become a standard, noninvasive method for determining the presence of a cervical HPV infection.

What is capture sequencing?

Sequence capture technology allows targeted enrichment of specific regions of a genome such as an entire exome. This, in concert with NGS, provides an efficient strategy for high-throughput screening of regions of interest, facilitating the identification and characterisation of physiologically relevant variants.

What does it mean when 2 strands of DNA hybridize ‘?

​Hybridization Hybridization, as related to genomics, is the process in which two complementary single-stranded DNA and/or RNA molecules bond together to form a double-stranded molecule. The bonding is dependent on the appropriate base-pairing across the two single-stranded molecules.