What is a thrombophilia screen?
The Thrombophilia Screen is a combination of tests designed to provide evidence of inherited deficiencies of naturally occurring anticoagulants; Antithrombin, Protein C, and Protein S.
Who should be tested for thrombophilia?
Current guidelines suggest that thrombophilia testing should be considered in the following situations: If you have a venous thrombosis or pulmonary embolus under the age of 40. If you have repeated episodes of venous thrombosis or pulmonary embolus or inflamed veins (thrombophlebitis).
Why thrombophilia test is done?
You should get a test for thrombophilia if: You have a strong family history of blood clots. You have clots without a known cause (no risk factors). You have clots in unusual locations.
What are symptoms of thrombophilia?
Symptoms of thrombophilia
- throbbing or cramping pain in 1 leg (rarely both legs), usually in the calf or thigh.
- swelling in 1 leg (rarely both legs)
- warm skin around the painful area.
- red or darkened skin around the painful area.
- swollen veins that are hard or sore when you touch them.
Who is at risk for thrombophilia?
Acquired risk determinants can significantly increase the thrombotic risk further during pregnancy and the puerperium. These include maternal age (≥35 years), caesarean section, obesity, high parity (≥4), infection, and a personal or family history of VTE.
What is the most common thrombophilia?
Factor V Leiden is the most common inherited form of thrombophilia. Between 3 and 8 percent of people with European ancestry carry one copy of the factor V Leiden mutation in each cell, and about 1 in 5,000 people have two copies of the mutation. The mutation is less common in other populations.
How do I know if I have thrombophilia?
Your doctor can check for thrombophilia with blood tests. They look for abnormal genes and specific antibodies. They measure levels of clotting proteins in your blood. Your doctor may recommend testing in order to decide on your treatment choices, such as what type of blood thinner and how long you should take it.