Does Wilms tumor relapse?
Wilms’ tumour is the most common renal cancer in childhood and about 15% of patients will relapse.
Why Wilms tumor is triphasic?
Comments: In its classic appearance, Wilms tumor is triphasic and consists of variable proportions of blastema, stroma, and epithelial cells. One component may dominate over others in a given case, resulting in biphasic and monophasic variants.
Is Wilms tumor curable?
Overall, about 9 of 10 children with Wilms tumors are cured. A great deal of progress has been made in treating this disease in recent decades. Much of this progress is the result of children with Wilms tumors taking part in clinical trials of new treatments.
Where does Wilms tumor metastasis?
The most common site of metastatic spread of Wilms tumor is the lungs; chest CT scan is the preferred imaging modality for evaluating this site. Other rare sites of metastases, such as the liver, are usually well evaluated with the initial abdominopelvic CT scan.
What is the prognosis for Wilms tumor?
The overall prognosis of Wilms Tumor is usually quite positive with more than 80% of all children diagnosed expecting to survive the disease long-term. With a timely diagnosis before the tumor has metastasized to other parts of the body the cure rate is even higher at 90% with standard treatment.
Can Wilms tumor be prevented?
The only known risk factors for Wilms tumors (age, race, gender, and certain inherited conditions) can’t be changed. There are no known lifestyle-related or environmental causes of Wilms tumors, so at this time there is no way to prevent most of these cancers.
Does Wilms tumor run in families?
Wilms tumor can also run in families, although this is rare. Talk to your doctor if you have any relatives who have had a Wilms tumor. If you do, the children in your family may need to have regular ultrasound exams of the abdomen.
What happens if Wilms tumor ruptures?
Preoperative tumor rupture may result in tumor spillage, thus altering the prognosis. The overall cure rate of Wilms tumor in low risk children has risen to more than 90%. Yet, in cases of post-traumatic tumor rupture the rate drastically falls. Computed tomography of the abdomen may help to identify the complication.
Are Wilms tumors hereditary?
Inheritance. Most cases of Wilms tumor are not caused by inherited genetic factors and do not cluster in families. Approximately 90 percent of these cancers are due to somatic mutations, which means that the mutations are acquired during a person’s lifetime and are present only in the tumor cells.